pca-peptide-smoothing-serum The mog peptide 35-55 mouse rat acetate is a critical reagent in neuroscience research, specifically for modeling experimental autoimmune encephalomyelitis (EAE), a condition that mimics aspects of multiple sclerosis in humans.Myelin Oligodendrocyte Glycoprotein35-55,mouse,rat(MOG 35-55) is a minor ...PeptideContent (by %N), ≥80%. Single Impurity (by HPLC), ≤1.0%. Assay ... This particular peptide fragment, derived from Myelin Oligodendrocyte Glycoprotein (MOG), plays a key role in inducing EAE in laboratory animals, primarily rodents like mice and rats. Researchers utilize this peptide to study the mechanisms of demyelination and neuroinflammation, seeking to understand the immune system's attack on the central nervous system.
Myelin Oligodendrocyte Glycoprotein (MOG) is a protein found in the myelin sheath, which insulates nerve fibers in the central nervous system.Myelin Oligodendrocyte Glycoprotein 35-55, mouse, rat The MOG peptide 35-55 represents a specific sequence within this larger protein that is known to be highly immunogenicMOG (35-55) mouse, rat (Myelin Oligodendrocyte .... When introduced into susceptible animal models, this peptide fragment triggers an autoimmune response, leading to the development of EAE.MOG (35-55) human – MEVGWYRPPFSRVVHLYRNGK The acetate form is common for its stability and solubility, facilitating its use in experimental settingsMOG(35-55)mouse,rat(MOG(35-55)) can be used for experimental autoimmune encephalomyelitis (EAE) modeling. For research use only. We do not sell to patients ....
EAE is the most widely used animal model for studying the pathogenesis and potential treatments for multiple sclerosis (MS). The induction of EAE using mog peptide 35-55 mouse rat acetate allows researchers to:
* Investigate Disease Mechanisms: By studying the immune cells and inflammatory mediators that target the myelin sheath after MOG peptide administration, scientists gain insights into the cellular and molecular processes underlying demyelinating diseasesMOG 35-55; N-Terminus: H ; Amount: 1 mg ; Counter Ion: TFA ; Protein: Myelin-oligodendrocyte glycoprotein ; Species:Mouse,Rat..
* Test Therapeutic Interventions: The model provides a platform for evaluating the efficacy of novel drugs and therapies aimed at preventing or reversing the damage caused by autoimmune attacks on the CNSMOG(35-55)acetate；MOG(35-55) (rat,mouse). Description.MOG（35-55) is a glycoprotein from human myelin oligodendrocyte (MOG) truncatedpeptides.. This includes testing immunomodulatory agents, neuroprotective compounds, and regenerative strategiesMOG peptide (35-55) , mouse, rat acetate (149635-73-4 Free base).
* Study T Cell Responses: The MOG peptide is a potent T cell antigen. Research using this peptide helps to elucidate the role of specific T helper cell subsets (like Th1 and Th17) and regulatory T cells in the development and resolution of autoimmune inflammation in the CNS.
While the mog peptide 35-55 mouse rat acetate is frequently used, it's important to note that variations may exist. The peptide sequence itself is conserved across species, but the immunogenic epitopes can differ slightly. Therefore, researchers often specify whether they are using a peptide derived from mouse or rat MOG, as subtle differences in antigen presentation or immune recognition can influence disease induction and severity. The term "acetate" refers to the counterion of the peptide, which is a common and stable form for peptide reagents.Myelin Oligodendrocyte Glycoprotein (MOG)peptide(35-55) ,mouse,rat acetateis a MOG peptide (35-55) derivative. MOG peptide (35-55) is a part of myelin ... Other forms, like trifluoroacetate salts, may also be encountered, each with slightly different properties.
The primary application of mog peptide 35-55 mouse rat acetate is in immunological and neurological research.Myelin Oligodendrocyte Glycoprotein Peptide (35-55) ... It is typically supplied as a purified peptide for in vitro and in vivo studies.作者：MV Jones·2008·被引用次数：119—... (MOG)peptide. Axon loss began before behavioral signs when T cell ...ratMBP model to the neurodegenerative relapsing–remitting SJLmousePLP model. When using this reagent, researchers must adhere to strict laboratory protocols, including proper handling, storage, and administration to achieve reproducible results. The concentration, purity, and formulation of the peptide are critical factors that can affect the outcome of EAE inductionBuy Mog 35 55 Peptide for Sale Online. Furthermore, understanding the specific genetic background of the mouse or rat strain used is crucial, as susceptibility to EAE can vary significantly between strains.MOG(35-55)acetate；MOG(35-55) (rat,mouse). Description.MOG（35-55) is a glycoprotein from human myelin oligodendrocyte (MOG) truncatedpeptides.
In conclusion, the mog peptide 35-55 mouse rat acetate is an indispensable tool for advancing our understanding of autoimmune demyelinating diseasesMOG(35-55) (Myelin Oligodendrocyte GlycoproteinPeptide(35-55),mouse,rat)acetateis a minor component of CNS myelin.MOG(35-55) (acetate) has .... Its ability to reliably induce EAE in rodent models provides a crucial avenue for exploring disease pathogenesis and developing effective therapeutic strategies for conditions like multiple sclerosis.
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